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InChi:InChI=1S/C27H44N4O5/c1-4-6-8-12-24(34)30-22(18-20-13-15-21(32)16-14-20)26(35)31-25(19(3)5-2)27(36)29-17-10-7-9-11-23(28)33/h13-16,19,22,25,32H,4-12,17-18H2,1-3H3,(H2,28,33)(H,29,36)(H,30,34)(H,31,35)/t19-,22-,25-/m0/s1

Based on current evidence, some other Clostridium species (e.g., Clostridium difficile ) may contribute to ADs by disrupting gut microbial homeostasis, secreting exotoxins, or exacerbating intestinal barrier dysfunction

In some embodiments, the otic composition or formulation comprises less than 0.1% by weight of water